Analysis of Convolutional Autoencoder and U-Net forBreast Tumor Detection in Mammogram Images
DOI:
https://doi.org/10.70716/reswara.v4i4.750Keywords:
mammogram, convolutional autoencoder, U-Net, image segmentation, streamlitAbstract
Breast cancer is one of the most frequently diagnosed cancers among women worldwide. Early detection through mammogram analysis is important, but manual interpretation can be challenging because of low image contrast and variability in radiological assessment. This study evaluates the implementation of Convolutional Autoencoder (CAE) and U-Net architectures for mammogram image analysis and integrates both models into a Streamlit-based web application. The CBIS-DDSM dataset was used, comprising 723 training images and 181 testing images. The research stages included preprocessing, model training, evaluation, result analysis, and web application implementation. The U-Net model achieved a Dice Score of 0.4186, an Intersection over Union (IoU) of 0.2647, a precision of 0.5254, a recall of 0.3479, an F1-score of 0.4186, and an accuracy of 0.8955. Meanwhile, the CAE model employed a reconstruction-error threshold for anomaly detection, producing a mean anomaly score of 1.4779% and identifying 31 anomalous images among the 181 test images, using a reported threshold of 1.7578%. These findings indicate that U-Net is suitable for supervised lesion segmentation and localization, whereas CAE provides an annotation-independent approach to reconstruction-based anomaly analysis. However, further evaluation is required to establish the reliability of anomaly detection and the clinical applicability of both models.
References
Añez, D., Conti, G., Uriarte, J. J., Serrano-Olmedo, J. J., Martínez-Murillo, R., & Casanova-Carvajal, O. (2025). Artificial intelligence pipeline for mammography-based breast cancer detection: An integrated systematic review and large-scale experimental validation. Medicina, 61(12), Article 2237. https://doi.org/10.3390/medicina61122237
Arnold, M., Morgan, E., Rumgay, H., Mafra, A., Singh, D., Laversanne, M., Vignat, J., Gralow, J. R., Cardoso, F., Siesling, S., & Soerjomataram, I. (2022). Current and future burden of breast cancer: Global statistics for 2020 and 2040. The Breast, 66, 15–23. https://doi.org/10.1016/j.breast.2022.08.010
Asmalinda, W., Jasmi, J., Setiawati, D., Khatimah, K., & Sapada, E. (2022). Deteksi dini kanker payudara menggunakan pemeriksaan payudara sendiri (SADARI). Jurnal Pengabdian Kepada Masyarakat (ABDIKEMAS), 4(1), 10–17. https://doi.org/10.36086/j.abdikemas.v4i1
Azad, R., Aghdam, E. K., Rauland, A., Jia, Y., Avval, A. H., Bozorgpour, A., Karimijafarbigloo, S., Cohen, J. P., Adeli, E., & Merhof, D. (2024). Medical image segmentation review: The success of U-Net. IEEE Transactions on Pattern Analysis and Machine Intelligence, 46(12), 10076–10095. https://doi.org/10.1109/TPAMI.2024.3435571
Bhat, G. R., Sethi, I., Sadida, H. Q., Rah, B., Mir, R., Algehainy, N., … Bhat, A. A. (2024). Cancer cell plasticity: From cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance. Cancer and Metastasis Reviews, 43(1), 197–228. https://doi.org/10.1007/s10555-024-10172-z
Brown, A. L., Vijapura, C., Patel, M., De La Cruz, A., & Wahab, R. (2023). Breast cancer in dense breasts: Detection challenges and supplemental screening opportunities. RadioGraphics, 43(10), Article e230024. https://doi.org/10.1148/rg.230024
Chatzara, A., Maliagkani, E., Mitsopoulou, D., Katsimpris, A., Apostolopoulos, I. D., Papageorgiou, E., & Georgalas, I. (2025). Artificial intelligence approaches for geographic atrophy segmentation: A systematic review and meta-analysis. Bioengineering, 12(5), Article 475. https://doi.org/10.3390/bioengineering12050475
Guo, S., Zhao, X., Ren, J., Shaw, M., Wan, J., & Su, J. (2026). Efficient cardiac MRI multi-structure segmentation for cardiovascular assessment with limited annotation by integrating data-level and network-level consistency. npj Digital Medicine, 9(1), 1–11. https://doi.org/10.1038/s41746-026-02475-y
Lepcha, D. C., Goyal, B., Dogra, A., Alkhayyat, A., Sahu, P. K., Ali, A., & Kukreja, V. (2025). Deep learning in medical image analysis: A comprehensive review of algorithms, trends, applications, and challenges. CMES—Computer Modeling in Engineering & Sciences, 145(2), 1487–1573. https://doi.org/10.32604/cmes.2025.070964
Li, J., Cheng, L., Xia, T., Ni, H., & Li, J. (2021). Multi-scale fusion U-Net for the segmentation of breast lesions. IEEE Access, 9, 137125–137139. https://doi.org/10.1109/ACCESS.2021.3117578
Luo, L., Wang, X., Lin, Y., Ma, X., Tan, A., Chan, R., Vardhanabhuti, V., Chu, W. C. W., Cheng, K. T., & Chen, H. (2025). Deep learning in breast cancer imaging: A decade of progress and future directions. IEEE Reviews in Biomedical Engineering, 18, 130–151. https://doi.org/10.1109/RBME.2024.3357877
Mienye, I. D., & Swart, T. G. (2025). Deep autoencoder neural networks: A comprehensive review and new perspectives. Archives of Computational Methods in Engineering, 32(7), 3981–4000. https://doi.org/10.1007/s11831-025-10260-5
Nomiko, D., Bar, A., Monalisa, M., & Eliezer, B. (2025). Effectiveness of risk detection application in breast cancer prevention in women of childbearing age. Health Education and Health Promotion, 13(1), 55–60. https://doi.org/10.58209/hehp.13.1.55
Nursoleha, E., & Utami, W. (2025). Bibliometric analysis of drug resistance biomarkers in breast cancer (2020–2025). International Journal of Applied Pharmaceutics, 17(4), 10–18. https://doi.org/10.22159/ijap.2025v17i4.54227
Parra-Cabrera, G., Jiménez-Delgado, J. J., & Pérez-Cano, F. D. (2026). Artificial intelligence for pulmonary abnormality detection in chest X-ray imaging: A detailed review of methods, datasets and future directions. Technologies, 14(3), Article 147. https://doi.org/10.3390/technologies14030147
Penedo, P., Machado, J., Anjos, R., Marta, A., Silva, A. C., & Cunha, A. (2026). Weakly supervised deep learning for ocular image segmentation: A systematic review of fundus and OCT methods. Applied Sciences, 16(5), Article 2241. https://doi.org/10.3390/app16052241
Saravana, S. K. (2023). Fundamentals of cancer biology. ResearchGate. https://www.researchgate.net/publication/371165300
Swiecicki, A., Konz, N., Buda, M., & Mazurowski, M. A. (2021). A generative adversarial network-based abnormality detection using only normal images for model training with application to digital breast tomosynthesis. Scientific Reports, 11(1), Article 1–13. https://doi.org/10.1038/s41598-021-89626-1
American Cancer Society. (n.d.). What is cancer? https://www.cancer.org/cancer/understanding-cancer/what-is-cancer.html
Zadeh, H. G., Fayazi, A., Binazir, B., & Yargholi, M. (2021). Breast cancer diagnosis based on feature extraction using dynamic models of thermal imaging and deep autoencoder neural networks. Journal of Testing and Evaluation, 49(3). https://doi.org/10.1520/JTE20200044
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Talitha Nirmala Neva, Zaenal Alamsyah, Nugraha (Author)

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.




